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Signet-Ring Cutaneous Metastasis Presenting with Huge Bunches of Grapes
Zhenyu Hao1, Yongqiong Deng1, Yuanmin He1
1Department of Dermatology STD, The Affiliated Hospital of Southwest Medical University, Luzhou, People's Republic of China.
Abstract:
Signet-ring cell (SRC) is a histologic type in which cells show unique features under the microscope. We mainly found signet-ring cells (SRCs) in gastrointestinal and breast tumors. Cutaneous metastasis from internal carcinomas was an uncommon presentation. The cases of signet-ring cell carcinoma (SRCC) metastasis to the skin were rarely reported. Cutaneous metastasis indicated a poor prognosis for a patient. Here, we report a female who had huge grape-like nodules arising from gastrointestinal SRCC in her trunk and thigh.
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