Related Experiment Video
Updated: Aug 26, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Systemic antibiotic sales and WHO recommendations, India
Aashna Mehta1, Petra Brhlikova2, Patricia McGettigan3
1Public Health Foundation of India, Gurugram, India.
Antibiotic sales in India show significant sales of "Watch" group antibiotics and unapproved fixed-dose combinations. Stricter enforcement and auditing of approvals are needed to align with World Health Organization (WHO) recommendations.
Area of Science:
- Pharmacology
- Public Health
- Health Policy
Background:
- Antibiotic resistance is a global health crisis.
- The World Health Organization (WHO) provides guidelines for antibiotic stewardship.
- India faces challenges in regulating antibiotic sales and use.
Purpose of the Study:
- To analyze antibiotic sales in India.
- To compare sales with WHO recommendations and national regulations.
- To investigate fixed-dose combination (FDC) antibiotic sales.
Main Methods:
- Extracted sales data for systemic antibiotics in India.
- Compared market share by WHO AWaRe (Access, Watch, Reserve) categories.
- Analyzed FDCs based on regulatory approval and essential medicine lists.
Main Results:
- 78 single and 112 FDC antibiotics were marketed, with high sales volumes.
- Access, Watch, and Reserve antibiotics constituted significant market shares.
- Many WHO not-recommended FDCs lacked formal approval, yet were top sellers.
Conclusions:
- Sales of 'Watch' group antibiotics require investigation and enforcement.
- Auditing the evidence for approvals of not-recommended FDCs is crucial.
- Regulatory efforts need strengthening to align with WHO guidelines.
More Related Videos
08:58Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
06:54Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
Published on: July 19, 2024
Related Concept Videos
Development of Antibiotic Resistance
Antimicrobial Effectiveness
Antibiotic Selection
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
International Nursing Organizations II
The WHO provides expert team support, including funding, vaccines, testing, and treatment tools at the country level to fight...