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Stability Over Time of In-Hospital-Compounded Amoxicillin Capsules and Ceftriaxone Patch Tests for Drug Allergy

H Gondé1,2, I Belaid1,3, F Lamoureux3

  • 1Department of Pharmacy, Rouen University Hospital, Rouen, France.

Journal of Investigational Allergology & Clinical Immunology
|October 4, 2022
PubMed
Summary

No abstract available in PubMed .

Keywords:
CapsulesDrug compoundingDrug stabilityPatch testsß-Lactams

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Allergic Drug Reactions01:27

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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