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The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
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In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
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Directing Effect of Substituents: meta-Directing Groups01:09

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Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
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Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...
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Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
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Valence Bond Theory

9.1K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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Directing metallo-supramolecular assembly through complementarity.

Jess L Algar1, Dan Preston1

  • 1Research School of Chemistry, Australian National University, Canberra, ACT, 2600, Australia. daniel.preston@anu.edu.au.

Chemical Communications (Cambridge, England)
|October 4, 2022
PubMed
Summary
This summary is machine-generated.

Chemists can now create complex molecular structures by controlling metallosupramolecular self-assembly. This involves using specific ligand arrangements to achieve desired low-symmetry or component-based architectures.

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Area of Science:

  • Chemistry
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Molecular function and behavior are intrinsically linked to their structure.
  • Developing complex functional molecules requires precise control over structural assembly.
  • Metallosupramolecular self-assembly often results in highly symmetric or statistical mixtures, hindering the creation of defined architectures.

Purpose of the Study:

  • To develop strategies for enforcing control in metallosupramolecular self-assembly.
  • To achieve the formation of highly ordered and defined architectures with low symmetry or lower symmetry components.
  • To overcome the inherent tendencies of self-assembled systems towards high symmetry or statistical mixtures.

Main Methods:

  • Utilizing complementary and orthogonal arrangements of ligands around a metal ion site.
  • Employing π-π interactions for additional conformational or geometric regulation.
  • Investigating methods to control connectivity in self-assembled systems.

Main Results:

  • Demonstrated successful control over the formation of defined metallosupramolecular architectures.
  • Achieved low-symmetry structures and architectures composed of lower symmetry components.
  • Established ligand arrangement as a key factor in directing self-assembly outcomes.

Conclusions:

  • Complementary and orthogonal ligand arrangements are effective for controlling metallosupramolecular assembly.
  • π-π interactions provide a means to further regulate the geometry and conformation of assembled structures.
  • These strategies enable the rational design and synthesis of complex, low-symmetry molecular architectures.