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Related Experiment Video

Updated: Aug 26, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

142

Cannabinoids in hyperhidrosis.

Till Kaemmerer1, Benjamin Maximilian Clanner-Engelshofen1, Tony Lesmeister1

  • 1Department of Dermatology and Allergy, University Hospital, LMU Munich, Munich, Germany.

The Journal of Dermatological Treatment
|October 6, 2022
PubMed
Summary
This summary is machine-generated.

Cannabinoids offer a novel, low-cost treatment for generalized hyperhidrosis, significantly reducing sweat volume and improving patient quality of life. This approach shows promise for refractory cases where other treatments failed.

Keywords:
Sweatcannabisdronabinoltetrahydrocannabinol (THC)

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Generalized hyperhidrosis significantly impacts patient quality of life, causing physical distress and social challenges.
  • Existing treatments for hyperhidrosis are frequently unsatisfactory, particularly for generalized forms of the condition.

Observation:

  • This study explored the use of cannabinoids as a treatment for refractory generalized hyperhidrosis.
  • An open trial design was employed to assess the efficacy of this novel therapeutic approach.

Findings:

  • Cannabinoid treatment resulted in a remarkable reduction in sweat volume.
  • Patients experienced significant improvements in their overall quality of life.

Implications:

  • Cannabinoids represent a promising, low-cost, and low-impact therapeutic option for generalized hyperhidrosis.
  • This approach may offer a viable alternative for patients with refractory symptoms unresponsive to conventional treatments.