Polypharmacy in Hospice and Palliative Care

Area of Science:

• Geriatrics
• Palliative Care
• Pharmacology

Background:

• Patients with limited life expectancy often have complex medication regimens.
• Revisiting treatment goals and patient preferences is crucial in end-of-life care.

Purpose of the Study:

• To discuss common medications suitable for deprescribing in palliative and hospice settings.
• To provide practical guidance and toolkits for deprescribing.

Main Methods:

• Literature review of common deprescribing strategies.
• Identification of frequently used medications in palliative care that can be discontinued.
• Development of a stepwise approach for medication withdrawal.

Main Results:

• Specific classes of medications commonly used in palliative care are identified for potential deprescribing.
• A structured approach to deprescribing, involving patient-clinician discussion and shared decision-making, is outlined.
• The importance of regular monitoring and follow-up during the deprescribing process is highlighted.

Conclusions:

• Deprescribing can improve quality of life and reduce medication burden in patients with limited life expectancy.
• A collaborative approach between clinicians and patients is essential for successful deprescribing.
• Toolkits and guidelines can support healthcare providers in implementing deprescribing interventions.