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[Pathophysiology and Role of Coronary CT Angiography in Stable Angina]

Jong Eun Lee, Hye Mi Park, Yongwhan Lim

    Taehan Yongsang Uihakhoe Chi
    |October 14, 2022
    PubMed

    Insights

    Coronary artery disease (CAD) management has evolved with the introduction of chronic coronary syndrome. Coronary CT angiography (CCTA) is crucial for early detection and characterizing plaque in CAD patients.

    Area of Science:

    • Cardiology
    • Radiology
    • Medical Imaging

    Context:

    • The clinical understanding of coronary artery disease (CAD) has significantly evolved.
    • Patients with CAD face risks of acute coronary syndromes throughout disease progression.
    • The 2019 European Society of Cardiology guidelines introduced "chronic coronary syndrome" to emphasize early diagnosis and management.

    Purpose:

    • To review the pathophysiology of stable angina.
    • To explain the clinical applications of coronary CT angiography (CCTA) in evaluating CAD.
    • To highlight CCTA's role in detecting early asymptomatic CAD and characterizing atherosclerotic plaque.

    Summary:

    • Coronary CT angiography (CCTA) offers significant advancements in evaluating coronary artery disease (CAD).
    • CCTA is valuable for detecting early, asymptomatic CAD and characterizing atherosclerotic plaques.
    • Understanding stable angina pathophysiology aids in appreciating CCTA's clinical utility across all CAD stages.

    Impact:

    • CCTA facilitates early diagnosis and risk stratification in patients with stable angina or chronic coronary syndrome.
    • Characterization of atherosclerotic plaque by CCTA informs treatment strategies for CAD.
    • This review enhances comprehension of CCTA's role in managing CAD, aligning with current clinical guidelines.

    Keywords:
    Angina, StableComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseasePlaque, Atherosclerotic

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