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Updated: Aug 25, 2025

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis

Aino Siltari1, Ragnar Lönnerbro2, Karl Pang3

  • 1Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Faculty of Medicine, Pharmacology, University of Helsinki, Helsinki, Finland.

Clinical Genitourinary Cancer
|October 15, 2022
PubMed
Summary

Polygenic risk scores (PRS) show modest ability in predicting prostate cancer (PCa) risk alone. Combining PRS with clinical data significantly improves PCa risk prediction accuracy in Caucasian men.

Keywords:
Genetic variancePolygenic risk scoreProstate cancer riskSingle-nucleotide polymorphism

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