Outcomes of a Comprehensive Mobile Smoking Cessation Program With Nicotine Replacement Therapy in Adult Smokers:...

Area of Science:

• Digital Health
• Behavioral Science
• Public Health

Background:

• Cigarette smoking is a leading cause of preventable death, necessitating effective evidence-based cessation solutions.
• Mobile health interventions offer scalable approaches to smoking cessation.
• Pivot is a comprehensive mobile program combining a CO sensor, app, human coaching, NRT, and community support.

Purpose of the Study:

• To compare the efficacy of the Pivot smoking cessation program against the National Cancer Institute's QuitGuide app.
• To evaluate differences in engagement, retention, attitudes, smoking behavior, and user feedback between Pivot and QuitGuide.
• To assess biovalidated cessation outcomes in a randomized controlled trial.

Main Methods:

• A remote pilot randomized controlled trial involving 188 adult smokers in the United States.
• Participants were randomized to either the Pivot program or the QuitGuide app for 12 weeks.
• Outcomes included self-reported app usage, point prevalence abstinence (PPA), continuous abstinence, and biovalidated CO levels.

Main Results:

• Pivot showed significantly higher engagement, with mean app openings at 12 weeks being 157.9 versus 86.5 for QuitGuide (P<.001).
• Biovalidated continuous abstinence rates at 26 weeks were higher for Pivot (21%) compared to QuitGuide (10%; P=.03).
• Participant feedback favored Pivot regarding ease of setup, impact on smoking, and likelihood of recommendation.

Conclusions:

• The Pivot mobile smoking cessation program demonstrated superior engagement and validated abstinence rates compared to QuitGuide.
• Pivot's comprehensive approach, including coaching and community support, contributes to its effectiveness.
• Findings support Pivot as a durable and effective mobile intervention for smoking cessation.