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Updated: Aug 25, 2025

Using Light Sheet Fluorescence Microscopy to Image Zebrafish Eye Development

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Published on: April 10, 2016

TriDFusion (3DF) image viewer.

Daniel Lafontaine¹, C Ross Schmidtlein², Assen Kirov²

¹Departments of Medical Physics, Memorial Sloan Kettering Cancer Center, 1250 First Avenue, New York, NY, 10065, USA. lafontad@mskcc.org.

|October 18, 2022

Summary

This summary is machine-generated.

The TriDFusion (3DF) image viewer is an open-source platform for nuclear medicine research, offering advanced tools for multi-modality image analysis and fusion. It provides researchers with enhanced capabilities for displaying, manipulating, and analyzing medical images.

Keywords:

DICOM viewer Medical image manipulation Molecular imaging software

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Area of Science:

Medical Imaging
Nuclear Medicine
Radiology

Background:

Nuclear medicine research often lacks advanced, integrated viewing platforms.
Commercial workstations have limitations for complex research imaging studies.
There is a need for extensible, open-source tools in medical image analysis.

Purpose of the Study:

To introduce the TriDFusion (3DF) image viewer, an open-source platform.
To address unmet needs in nuclear medicine research with advanced imaging tools.
To provide a vendor-neutral solution for multi-modality image analysis.

Main Methods:

Developed an extensible, open-source medical viewing platform (3DF).
Integrated image registration for multiple modalities with volumes of interest (VOIs) and dose distributions.
Included a high-quality viewer, multi-image fusion, segmentation tools, dosimetry, and clinical correction tools.
Wrote the software in MATLAB™ for readability and ease of modification.

Main Results:

The 3DF platform enables registration and fusion of images from different vendors.
Functional components include a viewer, multi-image fusion, segmentation, dosimetry, and error correction tools.
Output options include saving as DICOM files or exporting numerical results as CSV files.
The software facilitates complex clinical research workflows through its versatile tools.

Conclusions:

3DF offers a powerful, user-friendly, open-source suite for nuclear medicine research.
It empowers physicians, physicists, and researchers to effectively display, manipulate, and analyze medical images.
The platform enhances capabilities beyond those found in typical commercial workstations.