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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Updated: Aug 25, 2025

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

Deep Brain Stimulation Surgery Using a Mobile Intraoperative CT Scanner.

Daniel Cavalcante¹, Muhammad S Ghauri², Ryder Gwinn³

¹Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, USA.

|October 19, 2022

Summary

Intraoperative CT scans show accuracy comparable to traditional fixed CT for deep brain stimulation (DBS) electrode placement. This finding supports using intraoperative CT for precise DBS surgery planning and confirmation.

Keywords:

deep brain stimulation (dbs)euclidean distance intraoperative ct scanner leksell localizer box movement disorders

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Last Updated: Aug 25, 2025

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Published on: March 23, 2022

Area of Science:

Neurosurgery
Medical Imaging
Neurology

Background:

Deep brain stimulation (DBS) is a key treatment for movement disorders.
Accurate electrode placement is crucial for successful DBS outcomes.
Comparing imaging modalities is essential for optimizing surgical procedures.

Purpose of the Study:

To evaluate the accuracy of intraoperative CT scans versus traditional fixed CT for DBS electrode placement.
To compare pre-operative registration errors between intraoperative and fixed CT scanners.
To assess post-operative electrode positioning accuracy using both imaging methods.

Main Methods:

Retrospective analysis of 30 patients undergoing DBS surgery.
Group 1: 10 patients with fixed CT for pre- and post-operative imaging.
Group 2: 20 patients with intraoperative and fixed CT for pre- and post-operative imaging.

Main Results:

Mean registration error for intraoperative CT (Group 2) was 0.37, compared to 0.44 for fixed CT (Group 1).
The difference in pre-operative registration error was not statistically significant (p = 0.13).
Average Euclidean distance for electrode position confirmation in Group 2 was 0.36.

Conclusions:

Intraoperative CT accuracy is comparable to the gold standard fixed CT for DBS.
Intraoperative CT is suitable for both planning and post-operative confirmation of DBS electrode placement.
This validates intraoperative CT as a reliable tool in DBS procedures.