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Published on: August 28, 2020
[TETHERED CORD SYNDROME IN CHILDREN WITH DAYTIME INCONTINENCE]
Yosuke Morizawa1, Hiroyuki Satoh1, Atsuko Sato1
1Department of Urology, Tokyo Metropolitan Children's Medical Center.
Insights
Tethered cord syndrome can cause daytime urinary incontinence in children. Early diagnosis with spinal MRI and urodynamic testing, followed by surgery, leads to a complete cure for bladder dysfunction.
Area of Science:
- Pediatric Urology
- Neurology
- Spinal Cord Disorders
Context:
- Tethered cord syndrome (TCS) involves spinal cord fixation, leading to neurological deficits.
- Bladder dysfunction is a common early symptom in pediatric TCS.
- Daytime urinary incontinence in children warrants investigation for underlying neurological causes like TCS.
Purpose:
- To evaluate the efficacy of surgical untethering for daytime urinary incontinence in children diagnosed with TCS.
- To identify diagnostic methods, including spinal MRI and urodynamic testing, for TCS in pediatric patients with incontinence.
- To assess clinical outcomes and recovery rates following surgical intervention for TCS.
Summary:
- Eighteen children with daytime urinary incontinence and diagnosed TCS underwent surgical untethering.
- Spinal MRI identified various TCS subtypes, including filum lipoma and occult TCS.
- All patients achieved a cure for incontinence post-surgery, with some requiring additional management for nocturnal enuresis or catheterization.
Impact:
- Highlights the importance of considering TCS in children with unexplained daytime urinary incontinence.
- Demonstrates the effectiveness of surgical untethering in resolving bladder dysfunction associated with TCS.
- Emphasizes the role of urodynamic assessment and spinal MRI in diagnosing TCS.
Abstract:
(Introduction) In tethered cord syndrome, the lower end of the spinal cord is moored to the caudal tissue, causing various neuropathies. Bladder dysfunction often appears early. We herein evaluated children with daytime urinary incontinence in whom tethered cord syndrome was eventually diagnosed. (Method) Eighteen children (9 males and 9 females) with daytime urinary incontinence were enrolled between March 2011 and October 2017. The causes of their urinary incontinence were investigated using spinal MRI and changes in clinical symptoms before and after untethering surgery. (Results) The average age at the first visit was 6.3 years (range: 4-9 years). Urodynamic testing and a voiding cystourethrogram (VCUG) were performed in all cases of refractory daytime incontinence, and all patients with abnormal findings on either test underwent spinal MRI. The diagnosis based on spinal MRI findings was filum lipoma in eight, occult tethered cord syndrome in four, low set conus in four, conus lipoma in one, and sacral meningeal cyst in one, patient. The average observation period after untethering surgery was 66.3 months (range: 22-116 months). All the patients achieved a cure postoperatively. Four patients were treated for nocturnal enuresis by oral medication, and three patients required urological management via clean, intermittent catheterization. (Conclusions) When treating children with daytime continence, one should consider the possibility of tethered cord syndrome, the diagnosis of which can be aided by urodynamic assessment of bladder function.
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