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Multiplexed Chemical Sensing CMOS Imager.

Di Wang1,2, Libin Qian1, Fenni Zhang2,3

  • 1Intelligent Perception Research Institute, Zhejiang Lab, Hangzhou 311100, China.

ACS Sensors
|October 21, 2022
PubMed
Summary
This summary is machine-generated.

A new chemical sensing technology uses a complementary metal-oxide-semiconductor (CMOS) imager to create multiplexed colorimetric sensing chips. This innovation enables mobile health and Internet of Things applications through highly integrated, scalable chemical sensors.

Keywords:
chemical sensorcolorimetryminiaturized sensormultiplexed detectionnanocomposite

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Sensor Technology

Background:

  • Miniaturized and multiplexed chemical sensing is crucial for mobile devices and robots.
  • Current technologies face limitations in integration and scalability for widespread mobile applications.

Purpose of the Study:

  • To develop a miniaturized and multiplexed chemical sensing technology using complementary metal-oxide-semiconductor (CMOS) imagers.
  • To demonstrate the potential for mobile health and Internet of Things (IoT) applications.

Main Methods:

  • Coating micron-scale sensing spots containing nanocomposites of colorimetric probes and silica nanoparticles onto a CMOS imager surface.
  • Utilizing the inherent pixel array of CMOS imagers for multiplexed detection.
  • Developing a smartphone accessory integrating the chemical CMOS sensor.

Main Results:

  • Successfully transformed a CMOS imager into a multiplexed colorimetric sensing chip.
  • Achieved high-performance gas sensing with spot-size invariance down to ~10 μm.
  • Demonstrated personal health management via detection of gaseous biomarkers and pollutants using a smartphone accessory.

Conclusions:

  • The developed CMOS-based chemical sensor platform offers high scalability and integration for chemical sensing.
  • This technology is compatible with mobile electronics, enabling applications in personal health management.
  • The platform holds significant promise for the widespread adoption of chemical sensing in mobile and wearable devices.