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Updated: Aug 24, 2025

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An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
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Appendiceal adenocarcinoma presenting as a bladder tumor
Briana Goddard1, Ezra Baraban2, Darcy Wolfman2
1George Washington University Hospital, 900 23rd St NW, Washington, DC, 20037, USA.
Urology Case Reports
|October 24, 2022
Summary
Appendiceal adenocarcinoma can invade the urinary bladder, mimicking urachal tumors. This case highlights the importance of considering gastrointestinal origins for bladder adenocarcinoma.
Area of Science:
- Oncology
- Urology
- Gastroenterology
Background:
- Adenocarcinoma in the urinary bladder can present diagnostic challenges.
- Distinguishing primary bladder tumors from metastatic disease is crucial for appropriate treatment.
Observation:
- A patient presented with a suspected urachal adenocarcinoma.
- Surgical exploration revealed the tumor originated in the appendix and invaded the bladder.
Findings:
- Pathology confirmed appendiceal adenocarcinoma invading the bladder wall.
- The initial diagnosis of urachal adenocarcinoma was incorrect due to metastatic spread.
Implications:
- Urologists should maintain a high index of suspicion for gastrointestinal primary tumors when encountering bladder adenocarcinoma.
- This case underscores the need for thorough preoperative evaluation to identify the primary source of metastatic adenocarcinoma in the bladder.
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