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Updated: Aug 12, 2026

Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
Published on: July 29, 2012
Genetics and classification of major histocompatibility complex antigens of the chicken
Abstract:
The chicken MHC consists of a gene complex divisable into three chromosomal regions, each producing a series of genetically antithetical molecules with regionally specific functions. Most of the genes (alleles) of each region are present in unique haplotype combinations with genes (alleles) from the other two regions; relatively few haplotypes appear to share identical regional genes. Even with the high degree of polymorphism existing within and between regions, general typing of erythrocytes for MHC haplotypes can still be performed as economically as ever with alloimmune reagents of known specificity.
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