Nutraceuticals for Complementary Treatment of Multisystem Inflammatory Syndrome in Children: A Perspective from Their

Diego Estrada-Luna1, Elizabeth Carreón-Torres2, Susana González-Reyes3

  • 1Área Académica de Enfermería, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado Hidalgo, Circuito Ex Hacienda La Concepción S/N, Carretera Pachuca-Actopan, San Agustín Tlaxiaca 42160, Mexico.

Life (Basel, Switzerland)
|October 27, 2022
PubMed

Insights

Multisystem inflammatory syndrome in children (MIS-C) linked to SARS-CoV-2 infection presents with inflammation and cardiac issues. This review explores natural compounds as potential treatments to mitigate hyperinflammation damage in MIS-C.

Area of Science:

  • Pediatric infectious diseases
  • Cardiology
  • Immunology

Background:

  • Multisystem inflammatory syndrome in children (MIS-C) is a serious condition following SARS-CoV-2 infection.
  • MIS-C typically manifests 2-4 weeks post-infection with signs of inflammation and cardiac dysfunction.
  • Current treatments for MIS-C during the acute phase require further research for safety and effectiveness.

Purpose of the Study:

  • To review the potential of natural compounds in managing MIS-C.
  • To explore antioxidant and anti-inflammatory properties of natural compounds for MIS-C treatment.
  • To identify novel therapeutic interventions for reducing hyperinflammation-related damage in MIS-C.

Main Methods:

  • Literature review of existing studies on MIS-C.
  • Analysis of research on natural compounds with anti-inflammatory and antioxidant effects.
  • Synthesis of findings to propose potential treatment strategies for MIS-C.

Main Results:

  • MIS-C is characterized by significant inflammation and potential cardiac complications post-SARS-CoV-2.
  • Natural compounds possess antioxidant and anti-inflammatory properties that may counteract MIS-C pathology.
  • Evidence suggests natural compounds could mitigate collateral damage from hyperinflammation.

Conclusions:

  • Natural compounds offer a promising avenue for novel MIS-C treatments.
  • Targeting hyperinflammation with natural agents may reduce MIS-C severity.
  • Further research into natural compounds is crucial for developing effective MIS-C interventions.

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