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Materials Perspectives of Integrated Plasmonic Biosensors
Ayman Negm1,2, Matiar M R Howlader1, Ilya Belyakov3
1Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON L8S 4K1, Canada.
Materials (Basel, Switzerland)
|October 27, 2022
Summary
Plasmonic biosensors offer sensitive, label-free detection for portable devices. This review explores materials like 2D compounds and titanium nitride, and substrates for advanced biosensing applications.
Area of Science:
- Nanotechnology
- Biomedical Engineering
- Materials Science
Background:
- Plasmonic materials enable sensitive, label-free biosensing beyond light diffraction limits.
- There is a growing demand for portable, compact, low-cost, and efficient biosensors.
Purpose of the Study:
- To review the physical aspects of plasmonic interactions and materials for biosensors.
- To discuss substrates and factors influencing plasmonic biosensing mechanisms.
- To identify challenges and opportunities for widespread adoption of plasmonic biosensors.
Main Methods:
- Review of literature on plasmonic materials and biosensor design.
- Analysis of the role of 2D materials (graphene, transition metal dichalcogenides) in enhancing sensitivity.
- Evaluation of titanium nitride as a plasmonic material and polymer substrates for wearable devices.
Main Results:
- 2D materials significantly enhance nanoparticle-based plasmonic biosensor sensitivity.
- Titanium nitride shows promise for integrated applications, rivaling gold's performance.
- Polymer substrates are emerging for wearable and point-of-care plasmonic biosensor development.
Conclusions:
- Plasmonic biosensors, utilizing advanced materials and substrates, are poised for significant advancements.
- Addressing technical and economic challenges is crucial for mass adoption of these integrated biosensing technologies.
