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Feeding of Ticks on Animals for Transmission and Xenodiagnosis in Lyme Disease Research
Published on: August 31, 2013
[The Less Frequent Tick-borne Infections in Central Europe]
Rainer Weber1,2
1mediX Praxis Altstetten, Schweiz.
Abstract:
The Less Frequent Tick-borne Infections in Central Europe Abstract. The incidence of tick-borne infections is increasing, the endemic areas of tick vectors are expanding, novel tick-borne pathogens have been identified, and known pathogens are emerging in new geographic areas. This review focuses on the less frequent tick-borne pathogens in Central Europe, including Anaplasma, Babesia, Borrelia miyamotoi, Candidatus Neoehrlichia mikurensis, Ehrlichia, Francisella tularensis, Rickettsia, relapsing fever spirochetes, and tick-borne viruses. Travel-associated infections are also considered emphasizing a clinical and geographic approach. In addition to the most frequent Ixodes sp. also other tick species transmitting human pathogens are endemic in Europe. Clinicians should maintain suspicion for tick-borne diseases in patients presenting with fever of unexplained cause, with acute rash or with febrile neurological signs and symptoms. Because clinical manifestations of tick-borne infections are nonspecific - except for Erythema migrans - it is important to consider tick-borne illnesses even without a reported tick exposure or a suggesting travel history. Less than 50% of infected patients are aware of a tick-bite. Patients' history must include profession, leisure time activities, travel, and immune status. Tick-borne diseases may have a severe and life-threatening course in immunocompromised and splenectomized persons.
Insights
Tick-borne infections are rising in Central Europe, with less common pathogens like Anaplasma and Babesia emerging. Clinicians must suspect these diseases even without a known tick bite, especially in vulnerable patients.
Area of Science:
- Medical Entomology
- Infectious Diseases
- Public Health
Background:
- Tick-borne infections are increasing in Central Europe due to expanding vector ranges and emerging pathogens.
- This review details less frequent tick-borne pathogens, including Anaplasma, Babesia, Borrelia miyamotoi, Candidatus Neoehrlichia mikurensis, Ehrlichia, Francisella tularensis, Rickettsia, relapsing fever spirochetes, and tick-borne viruses.
Approach:
- Focuses on a clinical and geographic approach to tick-borne infections in Central Europe.
- Considers travel-associated infections and highlights the role of various tick species beyond Ixodes.
- Emphasizes the importance of a thorough patient history, including profession, leisure activities, travel, and immune status.
Key Points:
- Clinical manifestations are often nonspecific, necessitating a high index of suspicion for tick-borne diseases, even without a reported tick exposure.
- Less than 50% of infected individuals recall a tick bite.
- Immunocompromised and splenectomized individuals are at higher risk for severe and life-threatening outcomes.
Conclusions:
- Clinicians should consider tick-borne illnesses in patients with unexplained fever, rash, or neurological symptoms.
- Awareness of less common tick-borne pathogens and their varied presentations is crucial for timely diagnosis and treatment.
- Proactive patient history taking is essential for identifying potential exposures and risk factors.
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