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Predictive models for COVID-19 detection using routine blood tests and machine learning.
Yury V Kistenev1, Denis A Vrazhnov1, Ekaterina E Shnaider1
1Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, 36 Lenin Av., 634050 Tomsk, Russia.
Heliyon
|October 31, 2022
Summary
Developing accurate, fast, and inexpensive COVID-19 detection methods is crucial. This review explores using routine blood tests and machine learning to create predictive models for identifying SARS-CoV-2 infection.
Area of Science:
- Biomedical diagnostics
- Computational biology
- Infectious disease epidemiology
Background:
- Standard COVID-19 diagnostic tests are costly, time-consuming, and require specialized laboratory facilities.
- Routine blood tests offer a widely accessible and practical alternative for patient health assessment.
- Existing blood tests provide general health information, lacking direct specificity for SARS-CoV-2 infection.
Purpose of the Study:
- To review the potential of utilizing routine blood test data for detecting SARS-CoV-2 (the virus that causes COVID-19).
- To explore the development of predictive models for COVID-19 detection using machine learning algorithms.
- To identify specific blood characteristics indicative of SARS-CoV-2 invasion.
Main Methods:
- Literature review of studies on COVID-19 detection using routine blood parameters.
- Analysis of machine learning approaches for building predictive diagnostic models.
- Identification of key hematological markers associated with SARS-CoV-2 infection.
Main Results:
- Routine blood tests can be leveraged to develop cost-effective and rapid COVID-19 detection strategies.
- Machine learning models show promise in identifying COVID-19 specific patterns within standard blood test results.
- Selection of relevant blood markers is key for accurate predictive model development.
Conclusions:
- Predictive models based on routine blood tests and machine learning offer a feasible alternative to standard COVID-19 testing.
- This approach enhances accessibility to diagnostics, particularly in resource-limited settings.
- Further research is needed to refine models and validate their clinical utility for SARS-CoV-2 detection.

