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Published on: December 21, 2019
Phosphaturic mesenchymal tumor in right thigh: 2 cases report and literature review
Ruifeng Wang1,2, Jiayu Zhou1,2, Yupei Yu1,2
1Department of Pathology, Xiang-ya Hospital, Central South University, Changsha City, Hunan Province, China.
Background:
Phosphaturic mesenchymal tumor (PMT) is a very rare tumor of bone and soft tissue that has no specific clinical manifestations. Here we present 2 cases of PMT in the right thigh, including comparatively adequate immunohistochemistry.
Case Presentation:
We described 2 cases of PMT in the right thigh with manifestations of hypophosphatemia. PET-CT examination showed that both patients had lesions with increased expression of somatostatin receptors in the right thigh. Bland cells and dirty calcified stroma were exhibited under the microscope. And immunohistochemical detection of FGF-23 was positive.
Conclusions:
PMT is a very uncommon tumor for which diagnosis and treatment are often delayed. Considering the importance of surgery for the treatment of this disease, a full understanding of its clinicopathological features will facilitate the diagnosis of this disease.
