Visual Cu²⁺ Detection of Gold-Nanoparticle Probes and its Employment for Cu²⁺ Tracing in Circuit System

Highly sensitive, simple and reliable colorimetric probe for Cu²⁺-ion detection was visualized with the L-cysteine functionalized gold nanoparticle (LS-AuNP) probes. The pronounced sensing of Cu²⁺ with high selectivity was rapidly featured with obvious colour change that enabled to visually sense Cu²⁺ ions by naked eyes. By employing systemic investigations on crystallinities, elemental compositions, microstructures, surface features, light absorbance, zeta potentials and chemical states of LS-AuNP probes, the oxidation-triggered aggregation effect of LS-AuNP probes was envisioned. The results indicated that the mediation of Cu²⁺ oxidation coordinately caused the formation of disulfide cystine, rendering the removal of thiol group at AuNPs surfaces. These features reflected the visual colour change for the employment of tracing Cu²⁺ ions in a quantitative way.