PREVALENCE OF THE HERPES SIMPLEX VIRUS (TYPES 1 AND 2) AMONG PATIENTS IN THE PLACES OF DETENTION

Area of Science:

• Virology
• Epidemiology
• Public Health

Background:

• Herpes simplex virus (HSV) infections, particularly HSV-1 and HSV-2, are widespread globally.
• Understanding the seroprevalence and associated psychosocial factors within specific populations, like incarcerated individuals, is crucial for targeted public health interventions.

Purpose of the Study:

• To determine the serological prevalence of Herpes simplex 1 (HSV-1) and Herpes simplex 2 (HSV-2) among male and female prisoners in Ukraine.
• To analyze psychosocial aspects contributing to the spread of HSV infections within correctional facilities.

Main Methods:

• Blood serum samples were collected from 80 prisoners (40 men, 40 women) and analyzed for HSV-1 and HSV-2 specific IgM and IgG antibodies.
• A control group of 90 individuals (43 men, 47 women) from the general population was included for comparison.
• Social characteristics and history of herpetic manifestations were also recorded.

Main Results:

• High seroprevalence of IgG antibodies to HSV-1 and HSV-2 was observed in prisoners (95% overall).
• IgG to HSV-2 was significantly more prevalent in prisoners (2.5 times higher than the general population) and in women compared to men (1.5 times higher).
• IgM antibodies, indicating active infection, were detected only in the prisoner group, and active genital herpes was diagnosed in 17% of prisoners.

Conclusions:

• The prevalence of HSV-1 and HSV-2 is notably high among Ukrainian prisoners, with HSV-2 posing a greater concern compared to the general population.
• Factors such as female gender, age over 35, HIV infection, risky sexual behavior, substance abuse, and extensive tattoos are significant risk factors for HSV-2 infection in this population.
• The findings underscore the need for targeted prevention and management strategies for herpes simplex virus infections within correctional facilities.