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Related Concept Videos

Flail Chest-II01:26

Flail Chest-II

225
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
225
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

319
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
319
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

363
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
363
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

31
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
31
Flail Chest-I01:24

Flail Chest-I

260
Overview of Flail Chest
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...
260
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

19
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
19

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Related Experiment Video

Updated: Aug 23, 2025

Inducing Acute Lung Injury in Mice by Direct Intratracheal Lipopolysaccharide Instillation
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Flecainide-induced pneumonitis: a case report.

Gauthier Moureau1, Elies Zarrouk2, Delphine Hoton3

  • 1Department of Intensive Care, Cliniques St-Luc, Université catholique de Louvain, Avenue Hippocrate, 10, 1200, Brussels, Belgium.

Journal of Medical Case Reports
|November 2, 2022
PubMed
Summary

Flecainide therapy may cause acute respiratory distress, presenting as acute fibrinous and organizing pneumonia. This rare drug-induced lung injury, a diagnosis of exclusion, may improve with corticosteroids.

Area of Science:

  • Pulmonology
  • Toxicology
  • Pathology

Background:

  • Acute respiratory distress syndrome (ARDS) can be associated with drug toxicity.
  • Flecainide, an antiarrhythmic drug, has rarely been implicated in lung injury.
Keywords:
Acute fibrinous and organizing pneumoniaCorticosteroidsFlecainidePneumonitis

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