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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

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CHA2DS2-VASc score as a prognostic indicator in patients with atrial fibrillation undergoing coronary stenting

Jian-Yong Zheng1, Dong-Tao Li1, Yi-Gang Qıu1

  • 1Department of Cardiology, Division of Cardiology and Cardiovascular Surgery, Sixth Medical Center of PLA General Hospital, Beijing, China.

Turkish Journal of Medical Sciences
|November 3, 2022
PubMed

Insights

The CHA2DS2-VASc score accurately predicts adverse outcomes in patients with atrial fibrillation (AF) and coronary stenting. Higher scores correlate with increased risks of death, stroke, and major adverse cardiac events, confirming its prognostic value.

Area of Science:

  • Cardiology
  • Clinical Research
  • Medical Informatics

Background:

  • Patients with atrial fibrillation (AF) and coronary stenting face poor prognoses.
  • Assessing predictive accuracy of the CHA2DS2-VASc score in this high-risk population is crucial.

Approach:

  • Retrospective review of 2394 patients with nonvalvular AF undergoing coronary stenting (2010-2015).
  • Patients stratified into low (≤2), intermediate (3-4), and high (≥5) CHA2DS2-VASc score groups.
  • Major adverse cardiac/cerebrovascular events (MACCE) defined as composite of death, myocardial infarction, revascularization, and ischemic stroke/systemic thromboembolism (IS/SE).

Key Points:

  • All-cause mortality tripled from low to high CHA2DS2-VASc score groups (4.8% vs. 15.8%).
  • High score group (≥5) showed increased IS/SE (7.4%) and MACCE (26.3%).
  • CHA2DS2-VASc score ≥5 independently predicted all-cause death (HR 2.303), IS/SE (HR 4.169), and MACCE (HR 1.468).

Conclusions:

  • The CHA2DS2-VASc score demonstrates reliability in predicting adverse clinical outcomes for patients with AF and coronary stenting.
  • This score aids in risk stratification and management decisions for this vulnerable patient cohort.
Abstract

Keywords:
CHA2DS2-VASc scoreCoronary atherosclerotic diseaseatrial fibrillationpercutaneous coronary interventionprognosis

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