Related Experiment Video
Updated: Aug 23, 2025

Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells
Published on: September 5, 2017
Mechanical force induced DNA double-strand breaks: Ultrasound
1Faculty of Life and Medical Science, Doshisha University, Kyotanabe, Japan; Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Abstract:
Since the application of ultrasound for clinical diagnosis and therapeutic purposes has been increased rapidly, the effects of exposure to ultrasound on DNA molecules were studied. In this chapter, we introduced various effects of DNA damages caused by different conditions of exposure of ultrasound. Ultrasound with different sound pressure and pulse transmission conditions have been applied in our study. We discussed the threshold of sound pressure of ultrasound-induced DNA damages. Different kinds of pulses of ultrasound and microbubbles' influences on DNA double-strand breaks were also shown.
More Related Videos
Related Concept Videos
Fixing Double-strand Breaks
Homologous Recombination
Single-Strand DNA Binding Proteins
Nucleotide Excision Repair
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. ...

