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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Updated: Aug 23, 2025

A Melanoma Patient-Derived Xenograft Model

A Melanoma Patient-Derived Xenograft Model

Published on: May 20, 2019

Melanoma surgery-An update.

¹Department of Dermatology and Allergology, Municipal Hospital Dresden, Dresden, Germany.

Dermatologic Therapy

|November 7, 2022

Summary

This summary is machine-generated.

Surgery remains crucial for diagnosing and treating primary cutaneous melanoma. While its role evolves with new therapies, surgical techniques are becoming less invasive for targeted melanoma management.

Keywords:

cutaneous melanoma metastasectomy neoadjuvant therapy sentinel lymph node biopsy tumor surgery

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Last Updated: Aug 23, 2025

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Area of Science:

Oncology
Dermatology
Surgical Oncology

Background:

Cutaneous melanoma is a significant cause of skin cancer mortality.
Recent advancements include immunotherapy and targeted therapy for advanced melanoma (Stages III and IV).
The evolving landscape necessitates a redefinition of surgery's role in melanoma treatment.

Purpose of the Study:

To review the role of surgery in melanoma diagnosis and treatment.
To examine surgical approaches for primary tumors and metastases alongside new medical therapies.
To discuss emerging trends like neoadjuvant therapy and surgery for resistant metastases.

Main Methods:

Narrative review of current literature on surgical management of melanoma.
Analysis of surgical roles in the context of advanced medical treatments.
Discussion of ongoing clinical trials and future directions.

Main Results:

Surgery is essential for primary melanoma diagnosis and treatment.
Therapeutic lymphadenectomy's importance has diminished.
Sentinel lymph node biopsy and metastasectomy are valuable in personalized treatment plans.
A trend towards less invasive surgical procedures is observed.

Conclusions:

Surgery remains a cornerstone in the diagnosis and primary treatment of melanoma.
Surgical strategies are adapting to integrate with novel systemic therapies.
A personalized, less invasive surgical approach is key for optimal melanoma patient outcomes.