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Updated: Aug 23, 2025
08:12
A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
10.1K
2-({[(2S)-1-Hy-droxy-1,1,3-tri-phenyl-propan-2-yl]imino}-meth-yl)-4,6-bis-(4-methyl-phen-yl)phenol
Veronica L Show1, Emily Y Fok1, Adam R Johnson1
1Department of Chemistry, Harvey Mudd College, 301 Platt Blvd., Claremont, CA 91711, USA.
Iucrdata
|November 7, 2022
Summary
This study details the crystal structure of a novel organic compound (C42H37NO2). Intramolecular hydrogen bonds influence its molecular conformation and stability.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Understanding the solid-state structure of organic molecules is crucial for predicting their properties.
- Intramolecular interactions play a significant role in molecular conformation and reactivity.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C42H37NO2.
- To investigate the role of intramolecular hydrogen bonding in the compound's structure.
Main Methods:
- Single-crystal X-ray diffraction analysis.
- Crystallographic data collection and structure refinement.
Main Results:
- The compound crystallizes in the ortho-rhom-bic space group P212121.
- One molecule was observed in the asymmetric unit.
- Intramolecular hydrogen bonds were identified, involving the phenol hydroxyl group and the imine nitrogen, as well as the aliphatic alcohol and the imine nitrogen.
Conclusions:
- The crystal structure reveals specific intramolecular hydrogen bonding patterns.
- These interactions dictate the observed molecular conformation in the solid state.
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