Ethyl 1H-indole-2-carboxyl-ate
Will E Lynch1, Christine R Whitlock1, Clifford W Padgett1
1Georgia Southern University, Department of Chemistry and Biochemistry, Box 8064, Statesboro, GA 30460, USA.
Abstract:
Our work in the area of synthesis of tris indole compounds as a potential chelator led to the synthesis and crystallization of ethyl 1H-indole-2-carboxyl-ate, C11H11NO2, an indole that was synthesized by the thionyl chloride reaction of 1H-indole-2-carb-oxy-lic acid, followed by dissolution in ethanol. The mol-ecular packing exhibits a herringbone pattern with the zigzag running along the b-axis direction; the compound crystallizes as a hydrogen-bonded dimer resulting from O⋯H-N hydrogen bonds, between the indole N-H group and the keto oxygen atom, which build centrosymmetric R 2 2(10) ring motifs in the crystal.
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