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Updated: Aug 22, 2025
08:43
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
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2,6-Di-bromo-4-methyl-aniline.
Ouarda Brihi1, Meriem Medjani2, Hassiba Bougueria3
1Laboratoire de Cristallographie, Département de Physique, Université Frères Mentouri-Constantine 1, 25000 Constantine, Algeria.
Iucrdata
|November 7, 2022
Summary
This study reveals significant distortions in benzene ring bond angles within the C7H7Br2N compound. Molecular analysis also identified intramolecular N-H⋯Br contacts and intermolecular N-H⋯N hydrogen bonds forming crystal chains.
Area of Science:
- Crystallography
- Organic Chemistry
- Supramolecular Chemistry
Background:
- Distortions in aromatic ring geometry can influence molecular properties.
- Hydrogen bonding plays a crucial role in crystal packing and material characteristics.
Purpose of the Study:
- To characterize the crystal structure and intermolecular interactions of the title compound, C7H7Br2N.
- To investigate the impact of structural features on molecular assembly.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond angles, distances, and hydrogen bonding patterns was performed.
Main Results:
- The benzene ring in C7H7Br2N exhibits notable C-C-C bond angle distortions.
- Two short intramolecular N-H⋯Br contacts were observed within the molecule.
- Intermolecular N-H⋯N hydrogen bonds link molecules into C(2) chains along the [100] direction.
Conclusions:
- The crystal structure of C7H7Br2N is characterized by significant geometric distortions and specific hydrogen bonding motifs.
- These interactions dictate the formation of one-dimensional supramolecular chains in the solid state.
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