Related Experiment Video
Updated: Aug 22, 2025

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
A Quality Improvement Project to Decrease CLABSIs in Non-ICU Settings
Jill Engel1, Britt M Meyer, Gloria Alston McNeil
1Duke University Health System, Durham, North Carolina (Drs Engel and Granger); Duke University Hospital, Durham, North Carolina (Drs Meyer and Reynolds and Ms Bhandari); Duke Regional Hospital, Durham, North Carolina (Dr McNeil); Duke Raleigh Hospital, Raleigh, North Carolina (Dr Hicks); and Duke University School of Nursing, Durham, North Carolina (Drs Hatch, Granger, and Reynolds).
Implementing chlorhexidine gluconate (CHG) cloths for daily bathing in non-intensive care units significantly reduced central line-associated bloodstream infections (CLABSIs) by 22.8%, improving patient safety.
Area of Science:
- Healthcare-associated infection (HAI) prevention
- Quality improvement in nursing
- Evidence-based practice implementation
Background:
- Central line-associated bloodstream infections (CLABSIs) in non-intensive care units (non-ICUs) exceeded internal targets.
- A quality improvement (QI) initiative was launched by Doctor of Nursing Practice (DNP)-prepared nurse leaders to address this issue.
- The intervention focused on implementing 2% chlorhexidine gluconate (CHG) cloths for daily bathing of non-ICU patients with central lines.
Approach:
- A pre-post-design QI study was conducted across 34 non-ICU settings.
- Multifaceted educational strategies and electronic health record reminders supported CHG bathing implementation.
- Statistical process control (SPC) charts monitored CLABSI rates, and documentation compliance was audited.
Key Points:
- A 22.8% clinically significant reduction in CLABSI rates was observed post-intervention.
- CLABSI rates remained stable across the health system after implementation.
- CHG bathing documentation compliance improved from 77% to 94% system-wide.
Conclusions:
- The study supports the use of CHG cloths for daily bathing in non-ICU settings to reduce CLABSIs.
- Sustaining this practice change requires ongoing reinforcement through annual booster sessions.
- Nurse leaders reported satisfaction with the CHG bathing implementation process.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Health Information Technology and Healthcare Information System
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Endocarditis IV: Nursing Management
Nursing Interventions II: Selecting and Classifying the Nursing Interventions

