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Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study
Wala Al Balwi1, Maha Al Turki1, Ziad A Memish2
1College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Insights
A new Hajeer score combining age and body mass index (BMI) better predicts COVID-19 mortality risk than age alone. This score may improve risk stratification for coronavirus disease 2019 patients.
Area of Science:
- Epidemiology
- Public Health
- Gerontology
Background:
- Coronavirus disease 2019 (COVID-19) poses a significant global health threat.
- Understanding risk factors for COVID-19 mortality is crucial for patient management and public health strategies.
- The interplay between age, body mass index (BMI), and COVID-19 outcomes requires further investigation.
Purpose of the Study:
- To investigate the impact of age and BMI on COVID-19 mortality risk.
- To identify predictors of death in COVID-19 patients.
- To develop and validate a novel predictive score for COVID-19 mortality.
Main Methods:
- A cohort of 206 Saudi COVID-19 patients was analyzed.
- Data collected included age, BMI, hospitalization, comorbidities, and mortality.
- Descriptive, univariate, and multivariate logistic regression analyses were performed.
Main Results:
- Hypertension, cardiac disease, and hospital admission were significant predictors of death.
- Older age was a significant predictor of mortality.
- A novel age/BMI score (Hajeer score) demonstrated a stronger association with mortality than age alone.
Conclusions:
- Age and BMI are important factors influencing COVID-19 mortality.
- The newly proposed Hajeer score shows promise as a more potent predictor of death than age alone.
- Further validation in larger cohorts is recommended to confirm the utility of the Hajeer score.
Abstract:
The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analyzed. Descriptive, univariate, and multivariate logistic regression analyses were carried out. Out of the 206 studied patients, 28 died. Hypertension, cardiac disease, and hospital admission were predictors of death in univariate and multivariate logistic regression analysis. Moreover, age was a significant predictor of death, while increased BMI seemed to be protective at an older age. Therefore, a new score was suggested taking into consideration both factors, namely age/BMI score. Although older age was associated with death in univariate (OR, 1.09 [95% CI 1.05-1.12], p < 0.001) and multivariate analysis (OR, 1.05 [95% CI 1.02-1.09], p = 0.004), a higher age/BMI score was a stronger predictor of death than age alone, in both univariate (OR 4.42 [95% CI 2.50-7.80], p < 0.001) and multivariate analysis (OR 3.11 [95% CI 1.66-5.82], p < 0.001). Several factors appear to contribute to the risk of COVID-19 death. Interestingly, our new age/BMI score seems to carry a higher risk of death than age alone. This new score will be designated as the Hajeer score. Since this is a small cohort study, we recommend investigating this score in a larger cohort.
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