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Updated: Aug 21, 2025

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Published on: July 23, 2016
Describing Adverse Events Associated with Bilateral Same-Day Intravitreal Dexamethasone Implants
Background And Objectives:
To explore the incidence of adverse events after bilateral same-day intravitreal 0.7-mg dexamethasone implant (SDIDI) injections.
Materials And Methods:
We performed an IRB approved, single-center, retrospective review of patients receiving bilateral SDIDI injections from January 1, 2016 to October 31, 2021 and reviewed adverse events that occurred within 3 months of injection.
Results:
A total of 206 bilateral (412 eyes) SDIDI injections were performed in 59 patients. Ocular hypertension or the addition of intraocular pressure (IOP) lowering drops occurred in 121 (29.4%) eyes after IDI. Two (0.5%) eyes required glaucoma drainage surgeries. Of the 117 phakic eyes, 32 (27.4%) had progression of cataract or cataract extraction. There were two (0.5%) episodes of vitreous hemorrhage and one (0.2%) retinal tear with retinal detachment. There were no cases of endophthalmitis.
Conclusion:
Serious complication rates after bilateral same-day IDI injections appears low. Increased IOP that requires intervention can occur. [.
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