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Three New Lanostanoids with Anti-HCV Effects from Abies nukiangensis
Yong-Li Li1, Zhuo-Ni Xu1, Jie Li1
1Physical and Chemical Analysis laboratory, Shanghai Key laboratory of On-line Testing and Control Technology, Shanghai Institute of Measurement and Testing Technology, 1500 Zhangheng Road, Shanghai, 201203, China.
Abstract:
Three new lanostane derivatives (1-3) and twelve known triterpenoids (4-15) were isolated from the twigs and leaves of Abies nukiangensis. The structures of the new compounds were elucidated mainly by detailed analysis of their NMR and HR-ESI-MS spectroscopic data. Evaluation of the anti-HCV effects of all isolates showed that 3 exhibited moderate effect with the EC50 value of 11.09 μM.

