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Microfluidic quantum sensing platform for lab-on-a-chip applications.

R D Allert¹, F Bruckmaier¹, N R Neuling¹

¹Technical University of Munich, TUM School of Natural Sciences, Department of Chemistry, 85748 Garching b. München, Germany. dominik.bucher@tum.de.

|November 18, 2022

Summary

This summary is machine-generated.

This study introduces an integrated microfluidic platform for quantum sensors, enabling advanced chemical analysis in lab-on-a-chip devices. This innovation enhances miniaturization for applications in bioanalytics and single-cell studies.

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Area of Science:

Quantum Sensing
Microfluidics
Nanotechnology

Background:

Lab-on-a-chip (LOC) systems offer miniaturization benefits but require highly sensitive sensors.
Atom-sized quantum sensors enable nanoscale measurements but integrating them with LOC is technically challenging.

Purpose of the Study:

To develop a fully integrated microfluidic platform for solid-state spin quantum sensors.
To demonstrate the potential of quantum sensors in LOC for advanced chemical analysis.

Main Methods:

Developed a microfluidic platform compatible with nitrogen-vacancy (NV) centers in diamond.
Ensured platform capabilities for fast spin manipulation, biocompatibility, and adaptable geometries.
Demonstrated NV center-based sensing modalities including paramagnetic ion detection and microscale NV-NMR.

Main Results:

Successfully integrated solid-state spin quantum sensors into a microfluidic LOC platform.
Achieved full quantum sensing capabilities within the microfluidic environment.
Showcased diverse chemical analysis applications, from ion detection to high-resolution NMR.

Conclusions:

The integrated platform overcomes technical hurdles in combining LOC and quantum sensing.
Opens new avenues for chemical analysis in LOC devices.
Enables applications in electrochemistry, high-throughput screening, bioanalytics, and single-cell studies.