Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exceptions to the Octet Rule02:55

Exceptions to the Octet Rule

28.8K
Many covalent molecules have central atoms that do not have eight electrons in their Lewis structures. These molecules fall into three categories:
28.8K
Resonance02:52

Resonance

54.8K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds. 
54.8K
Lewis Structures of Molecular Compounds and Polyatomic Ions02:54

Lewis Structures of Molecular Compounds and Polyatomic Ions

35.1K
To draw Lewis structures for complicated molecules and molecular ions, it is helpful to follow a step-by-step procedure as outlined:
35.1K
Formal Charges02:42

Formal Charges

32.9K
In some cases, there are seemingly more than one valid Lewis structures for molecules and polyatomic ions. The concept of formal charges can be used to help predict the most appropriate Lewis structure when more than one reasonable structure exists.
32.9K
Nitric Oxide Signaling Pathway01:28

Nitric Oxide Signaling Pathway

5.1K
Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure...
5.1K
The Equilibrium Constant03:10

The Equilibrium Constant

48.5K
Consider the oxidation of sulfur dioxide:
48.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Local ordering of dimethylformamide around graphene oxide.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2026
Same author

Visualising reaction complexes in amine-based unloaded and CO<sub>2</sub>-loaded carbon capture solutions.

Nature communications·2026
Same author

Cooperation-Enhanced N-H···π Hydrogen Bonds: Liquid Pyrrole and Its Mixture with Benzene.

The journal of physical chemistry letters·2026
Same author

Stacking structure in liquid polyaromatic hydrocarbons.

Chemical communications (Cambridge, England)·2026
Same author

Molecular and pore-scale structure evolution in amorphous solid water.

Physical chemistry chemical physics : PCCP·2025
Same author

Lithium solvation and anion-dominated domain structure in water-in-salt electrolytes.

EES batteries·2025

Related Experiment Video

Updated: Aug 20, 2025

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
08:23

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds

Published on: February 16, 2022

4.3K

Microscopic Structure of Liquid Nitric Oxide.

Sarantos Marinakis1,2, Cillian Cockrell3, Kostya Trachenko3

  • 1Department of Chemistry, University of Patras, PatrasGR-26504, Greece.

The Journal of Physical Chemistry. B
|November 18, 2022
PubMed
Summary

Nitric oxide (NO) primarily exists as dimers in its liquid phase at low temperatures. Increasing temperature causes more NO dimers to dissociate into monomers, a trend confirmed by neutron scattering.

More Related Videos

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
08:25

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method

Published on: December 25, 2016

22.6K
Analytical Techniques for Assaying Nitric Oxide Bioactivity
11:28

Analytical Techniques for Assaying Nitric Oxide Bioactivity

Published on: June 18, 2012

18.1K

Related Experiment Videos

Last Updated: Aug 20, 2025

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
08:23

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds

Published on: February 16, 2022

4.3K
Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
08:25

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method

Published on: December 25, 2016

22.6K
Analytical Techniques for Assaying Nitric Oxide Bioactivity
11:28

Analytical Techniques for Assaying Nitric Oxide Bioactivity

Published on: June 18, 2012

18.1K

Area of Science:

  • Physical Chemistry
  • Materials Science
  • Chemical Physics

Background:

  • Understanding the microscopic structure of liquid nitric oxide (NO) is crucial for various chemical and physical applications.
  • Previous studies on NO's liquid phase structure have provided limited insights into molecular aggregation and dissociation.
  • Investigating NO's behavior under varying temperature and pressure conditions is essential for its industrial and scientific utilization.

Purpose of the Study:

  • To investigate the microscopic structure of liquid nitric oxide (NO) using advanced neutron scattering techniques.
  • To determine the dominant molecular forms (monomers, dimers, oligomers) of NO in the liquid phase across a range of temperatures and pressures.
  • To analyze the temperature-dependent dissociation of NO dimers into monomers and compare findings with existing literature.

Main Methods:

  • Neutron scattering experiments were conducted on liquid nitric oxide (NO) at temperatures ranging from 120 to 144 K and pressures from 1.1 to 9 bar.
  • Empirical Potential Structure Refinement (EPSR) technique was employed to analyze the scattering data and model the microscopic structure.
  • Molecular dynamics simulations were performed to validate the EPSR results and compare them with a previously proposed intermolecular potential for liquid NO.

Main Results:

  • At 120 K, liquid nitric oxide (NO) predominantly exists as dimers (approximately 80%), with a smaller fraction of monomers.
  • The degree of dimer dissociation into monomers increases significantly with rising temperature.
  • The diffraction data supports the presence of nonplanar dimers and does not rule out the formation of longer NO oligomers.

Conclusions:

  • The study confirms that nitric oxide (NO) exists mainly as dimers in the liquid phase at lower temperatures, dissociating into monomers as temperature increases.
  • The observed dissociation trend aligns with previous experimental findings and theoretical predictions.
  • The possibility of complex oligomeric structures in liquid NO warrants further investigation.