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Updated: Aug 20, 2025
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Management of Episodic Migraine with Neuromodulation: A Case Report
Thiago D Nascimento1, Dajung J Kim1, Conrad Chrabol1
1Department of Biologic and Materials Sciences & Prosthodontics, University of Michigan School of Dentistry, Ann Arbor, MI, USA; Michigan Neuroscience Institute (MNI), Headache & Orofacial Pain Effort (H.O.P.E.) Laboratory, 205 Zina Pitcher Pl, Room 1027, Ann Arbor, MI 48109, USA.
Abstract:
Migraine is a highly prevalent neurovascular disorder that affects approximately 15% of the global population. Migraine attacks are a complex cascade of neurologic events that lead to debilitating symptoms and are often associated with inhibitory behavior. The constellation of severe signs and symptoms during the ictal phase (headache attack) makes migraine the third most common cause of disability globally in both sexes under the age of 50. Misuse of pharmaceuticals, such as opiates, can lead to devastating outcomes and exacerbation of pain and headache attacks. A safe and well-tolerated non-pharmacological research approach is high-definition transcranial direct current stimulation over the M1.
