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Quincke's Disease Presenting After Cocaine Exposure
Filipa Madalena F Gonçalves1, Magda Costa2, Ana Luísa Campos2
1Internal Medicine, Hospital Senhora da Oliveira Guimarães, Guimaraes, PRT.
Cureus
|November 23, 2022
Summary
Quincke's disease, a rare upper airway swelling, can be triggered by various factors. This case highlights isolated uvular edema in a young man following cocaine use, emphasizing a potential new cause.
Area of Science:
- Otorhinolaryngology
- Emergency Medicine
Background:
- Quincke's disease is a rare condition involving localized angioedema of the upper airway.
- The epidemiology and precise causes of Quincke's disease are not well-documented due to its rarity.
Observation:
- A 27-year-old male presented with isolated uvular edema.
- The patient reported recent cocaine exposure prior to symptom onset.
Findings:
- This case presents a potential association between recreational cocaine use and the development of Quincke's disease.
- Isolated uvular edema can be a presenting symptom of this rare angioedema.
Implications:
- Cocaine use should be considered as a potential trigger for Quincke's disease.
- Further research is needed to elucidate the link between substance abuse and angioedema.
- Awareness among emergency physicians is crucial for prompt diagnosis and management.

