[Optimization of the drug treatment of hypertension]

The disclosure of clinico-pathogenetic variants of hypertensive disease led to the development of differentiated therapy. The use of mathematical methods of estimating the treatment schedule with dynamic control and correction (optimization) is very useful in differentiated therapy; with this technique the important principle of treatment, individualization, is applied most adequately. The main principles of conducting optimized therapy are discussed and the fields in which its use is most expedient are indicated. Some results gained by clinics carrying out research in this direction are discussed.