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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

24
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

19
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Transcutaneous Microcirculatory Imaging in Preterm Neonates
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Severe Thromboses in Neonates.

Matthew A Saxonhouse1, Ashley Hinson1

  • 1Wake Forest School of Medicine, Charlotte Campus, Levine Children's Hospital Atrium Health, Charlotte, NC, United States.

Current Pediatric Reviews
|November 25, 2022
PubMed
Summary

Severe neonatal thrombosis poses diagnostic challenges. This review discusses aortic, atrial, and septic thromboses in neonates and explores potential therapeutic benefits due to limited data.

Keywords:
Thrombosisanticoagulantclinician thrombophlebitisdiagnostic challengeneonatethromboses

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Area of Science:

  • Neonatal Medicine
  • Pediatric Thrombosis
  • Clinical Challenges

Background:

  • Severe thrombosis in neonates presents significant diagnostic and therapeutic challenges.
  • Specific conditions like aortic thrombosis, large right atrial thrombosis, and septic thrombophlebitis require careful management.
  • Limited data exists on optimal treatment strategies for these severe neonatal thrombotic events.

Approach:

  • This review synthesizes current understanding of severe neonatal thromboses.
  • It examines distinct clinical presentations including aortic, atrial, and septic thromboses.
  • Potential therapeutic interventions and their benefits are discussed.

Key Points:

  • Neonatal thrombosis requires careful risk-benefit assessment for treatment decisions.
  • Aortic thromboses, large right atrial thromboses, and septic thrombophlebitis are critical conditions.
  • Management necessitates appropriate clinical settings and subspecialty support.

Conclusions:

  • Further research is needed to establish ideal therapeutic guidelines for severe neonatal thrombosis.
  • Understanding these specific thrombotic conditions is crucial for effective clinical management.
  • This review aims to inform clinicians about potential benefits of various therapies.