Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Muscles that Move the Leg

Muscles that Move the Leg

The movement of the legs is facilitated by numerous muscles located within the anterior, medial, and posterior compartments of the thigh.
Anterior Compartment
The quadriceps femoris, the most visible muscle of the anterior compartment, is integral for leg extension and thigh flexion. It is formed by merging four distinct muscles — the vastus lateralis, vastus medialis, vastus intermedius, and rectus femoris. The quadriceps tendon, a shared tendon of the four quadriceps muscles, is affixed...

Muscles of the Leg that Move the Foot and Toes

Muscles of the Leg that Move the Foot and Toes

The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....

Varicose Veins I: Introduction

Varicose Veins I: Introduction

Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...

Indeterminate Structure

Indeterminate Structure

Indeterminate structures refer to structures where internal forces and reactions cannot be determined using only the equations of static equilibrium. Indeterminate structures have more unknown forces and reaction forces than equations of static equilibrium that can be used to determine them. Indeterminate structures are often used in engineering to create complex, efficient, and aesthetically pleasing structures. There are various types of indeterminate structures used in engineering and...

Assessing Blood pressure in the Leg

Assessing Blood pressure in the Leg

Proper measurement of leg blood pressure is a critical skill for healthcare providers, ensuring precise and reliable readings. When performed correctly, this procedure informs patient care and enhances the efficacy of interventions. The following text outlines step-by-step guidelines to measure blood pressure in the leg, providing clarity and ease of understanding for practitioners.
Preparation:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predicting first-trimester pregnancy outcome in threatened miscarriage: A comparison of a multivariate logistic regression and machine learning models.

Radiography (London, England : 1995)·2025

Same author

First-trimester bleeding: Can ultrasound and biochemical developmental markers deepen our understanding of threatened miscarriage?

Radiography (London, England : 1995)·2025

Same author

Known Unknowns: Making Sense of Head and Neck Squamous Cell Carcinoma of Unknown Primary.

Clinical oncology (Royal College of Radiologists (Great Britain))·2025

Same author

Efficacy of adjuvant therapy in patients with stage IIIA cutaneous melanoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2025

Same author

Assessing the predictive value of first trimester ultrasound and biochemical markers in miscarriage: A scoping review.

Radiography (London, England : 1995)·2024

Same author

What Matters to Aboriginal and Torres Strait Islander Youth (WM2Y): a study protocol to develop a national youth well-being measure.

BMJ open·2024

Same journal

Procalcitonin use in Acute Medicine in the United Kingdom: a survey of practice, barriers and facilitators.

Acute medicine·2026

Same journal

What does a job in Acute Medicine look like? Insights from the RCP 2023 Workforce Census.

Acute medicine·2026

Same journal

Embedding penicillin de-labelling in the AMU: a feasibility and safety pilot study with exploratory economic and environmental analysis.

Acute medicine·2026

Same journal

'Not All Swellings Are Angioedema' - An Overview And Systematic Approach For Acute Medical Physicians.

Acute medicine·2026

Same journal

The experiences of international medical graduates (IMGs) new to the NHS: an interpretive phenomenological analysis.

Acute medicine·2026

Same journal

Editorial - Differential attainment in training in the United Kingdom.

Acute medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 20, 2025

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

Weak legs.

P Timmons¹, A Williamson², V Gibbs³

¹MRCP, MBChB, Bsc (Med Sci), CDF in Acute Internal Medicine, Forth Valley Royal Hospital, Larbert.

|November 25, 2022

Summary

This summary is machine-generated.

A 48-year-old woman experienced progressive myalgia and muscle weakness, leading to falls. This case highlights potential drug-induced myopathy in patients with cardiovascular risk factors and psychiatric conditions.

More Related Videos

Muscle Imbalances: Testing and Training Functional Eccentric Hamstring Strength in Athletic Populations

Muscle Imbalances: Testing and Training Functional Eccentric Hamstring Strength in Athletic Populations

Published on: May 1, 2018

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Published on: November 11, 2022

Related Experiment Videos

Last Updated: Aug 20, 2025

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running

Published on: July 17, 2020

Muscle Imbalances: Testing and Training Functional Eccentric Hamstring Strength in Athletic Populations

Muscle Imbalances: Testing and Training Functional Eccentric Hamstring Strength in Athletic Populations

Published on: May 1, 2018

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Quantifying Arms and Legs Contributions during Repetitive Electrically-Assisted Sit-To-Stand Exercise in Paraplegics: A Pilot Study

Published on: November 11, 2022

Area of Science:

Neurology
Pharmacology
Rheumatology

Background:

The patient has a history of bipolar disorder and stroke, indicating potential neurological and cardiovascular vulnerabilities.
Current medications include clopidogrel, atorvastatin, and quetiapine, which have known side effect profiles.

Observation:

A 48-year-old female presented with a 7-week history of generalized myalgia and progressive muscle weakness.
The myopathy resulted in recurrent falls, significantly impacting her mobility and daily activities.

Findings:

The constellation of symptoms suggests a potential drug-induced myopathy, possibly related to statin therapy (atorvastatin) or other concurrent medications.
Further investigation is warranted to determine the exact etiology and differentiate from other causes of myalgia and weakness.

Implications:

This case underscores the importance of considering drug-induced myopathy in the differential diagnosis of new-onset myalgia and weakness.
Careful medication review and monitoring are crucial, especially in patients with multiple comorbidities and polypharmacy.