Technical Complications of Coronary Bifurcation Percutaneous Interventions
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Updated: Aug 19, 2025

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Gianluca Rigatelli1, Marco Zuin2, Dobrin Vassilev3
1Interventional Cardiology Unit, Division of Cardiology, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
Insights
Coronary bifurcation percutaneous interventions (PCI) present unique challenges. This paper details rare intraprocedural complications during PCI of coronary bifurcations, aiding cardiovascular professionals in patient management.
Area of Science:
- Interventional Cardiology
- Cardiovascular Disease Management
Background:
- Coronary artery disease involving bifurcations poses significant challenges.
- Percutaneous coronary interventions (PCI) for bifurcations are complex.
- Existing research often overlooks specific intraprocedural complications.
Purpose of the Study:
- To define and classify rare intraprocedural complications during coronary bifurcation PCI.
- To provide insights into the management and treatment of these complications.
- To enhance understanding for cardiovascular professionals managing bifurcation disease.
Main Methods:
- Review of clinical data and literature on coronary bifurcation PCI.
- Classification of reported intraprocedural technical complications.
- Analysis of treatment strategies for identified complications.
Main Results:
- Identification and categorization of various rare technical complications specific to bifurcation PCI.
- Discussion of the clinical implications and outcomes associated with these complications.
- Outline of effective management and treatment approaches.
Conclusions:
- Intraprocedural complications in coronary bifurcation PCI, though rare, require thorough understanding.
- Standardized classification and management strategies are crucial for improving patient outcomes.
- This review expands knowledge on managing complex bifurcation interventions.
Abstract:
Coronary bifurcation percutaneous interventions (PCI) comprise a challenging subset of patients with coronary artery disease. Beyond the well-known debate about single versus double stent strategies, which have different outcomes on mid- and long-term follow up, both strategies may be subject, although rarely, to several different technical complications, rarely reported in clinical trials, which need to be defined, classified, and understood by cardiovascular professionals involved in the management of patients with coronary bifurcation disease. The present paper aims to broaden the knowledge of the range of intraprocedural complications and relative treatment during PCI of coronary bifurcations.
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