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Access and Management of Sweat for Non-Invasive Biomarker Monitoring: A Comprehensive Review
Tamoghna Saha1, Rafael Del Caño1,2, Ernesto De la Paz1
1Department of Nanoengineering, University of California San Diego La Jolla, California, CA, 92093, USA.
This review explores sweat collection and management for advanced wearable sensors. It details sweat mechanisms and applications for personalized healthcare monitoring.
Area of Science:
- Biomedical Engineering
- Wearable Technology
- Biofluid Analysis
Background:
- Sweat regulates body temperature and contains blood biomarkers, making it accessible for health monitoring.
- Current sweat sensing devices focus on sensor development and short-term trials, limiting their clinical application.
Purpose of the Study:
- To provide a comprehensive review of sweat access and management techniques for improved sweat collection and sensing.
- To discuss advanced applications of sweat sensing and the development of robust epidermal wearable devices.
Main Methods:
- Review of sweat secretion mechanisms and historical perspectives.
- Detailed discussion on sweat generation and management on the skin.
- Analysis of current advancements in sweat sensing technologies and wearable devices.
Main Results:
- Identified key approaches for effective sweat collection and management from the skin.
- Highlighted the potential of sweat biomarkers for non-invasive health monitoring.
- Showcased the development of advanced epidermal wearable devices for continuous monitoring.
Conclusions:
- Improved sweat management is crucial for advancing sweat sensing technology.
- Wearable sweat sensing holds significant promise for personalized healthcare and continuous monitoring.
- Further development of robust, long-term wearable devices is needed to realize the full potential of sweat-based diagnostics.
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