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Updated: Aug 19, 2025

Measurement of Lifespan in Drosophila melanogaster
Published on: January 7, 2013
Time-resolved dynamic disability adjusted life-years estimation
Klaas De Jonge1,2, Jelle Laverge2
1FWO - Flanders Research Foundation, Brussels, Belgium.
Abstract:
The quantification of how healthy the indoor air is, is a complex issue comprising of a large number of contaminants of various sources. The health implication of exposure to each of the contaminant deemed of importance can be expressed using Disability Adjusted Life Years (DALYs). The sum of all DALYs indicates how harmful the indoor air was during the investigated time-frame. This metric was originally developed by the World Bank and the WHO. In 2012, Logue et. al described two methods to estimate the DALYs related to exposure to contaminants in the indoor air based on the yearly mean exposure concentration of a population. The downside of these methods is that, when detailed exposure concentration profiles are available the method results in a loss of information. A novel method was developed to estimate DALYs originating from exposure to indoor pollutants that can be used for time-resolved exposure concentration data without this loss of information: Dynamic DALYs. The advantage of this method is that it can be calculated in real-time and for short or long periods of data. As such it can be used for pin-pointing problematic events in the exposure profile of a person and, as it can be calculated in real-time, makes it a candidate for use in automated optimization problems. The use of Dynamic DALYs is demonstrated for a simulation case-study of an occupied apartment. One continuously ventilated system (Dcont) and one smart ventilation system (Dsmart) are compared. Sources of typically indoor generated Volatile Organic Compounds (VOCs) were added and the related exposure profile and Dynamic DALY results of the working adult were analyzed. The results showcase detailed and more summative results with regards to health and energy use using the novel indicator. For Dcont and Dsmart the total Dynamic DALYs are 2.2 years and 8.6 years, respectively (population of 100 000, duration of 1 year), for the VOCs and sources considered in the analysis.
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