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PANS-PANDAS, case report.

Francy Tatiana Villabona1, Gisela Hernández1, Víctor Manuel Mora-Bautista1

  • 1Clínica San Luis, Bucaramanga, Santander, Colombia.

Revista Colombiana De Psiquiatria (English Ed.)
|November 29, 2022
PubMed
Summary

Childhood acute neuropsychiatric syndrome (CANS) and pediatric acute-onset neuropsychiatric syndrome (PANS) are often missed diagnoses. Evaluating children with OCD or eating disorders for CANS/PANS is crucial for timely treatment and reduced morbidity.

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PANS-PANDAS, Case Report.

Revista Colombiana de psiquiatria (English ed.)·2021
Same author

17-hydroxiprogesterone values in healthy preterm infants.

Colombia medica (Cali, Colombia)·2018
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Area of Science:

  • Pediatric Neurology
  • Neuropsychiatry
  • Autoimmune Disorders

Background:

  • Childhood neuropsychiatric syndromes, including PANS and CANS, have evolved conceptually since 1980.
  • Despite recognition for over two decades, these conditions remain frequently undiagnosed by healthcare professionals.

Observation:

  • A case study of a 6-year-old girl presenting with acute onset of eating refusal.
  • The patient met diagnostic criteria for PANS-PANDAS and exhibited a relapsing-remitting course.
  • Initial treatments were ineffective, highlighting diagnostic challenges.

Findings:

  • The clinical history and presentation were consistent with PANS-PANDAS criteria.
  • The patient's condition demonstrated a relapsing-remitting pattern, a known characteristic of the syndrome.
Keywords:
Infecciones estreptocócicasPaediatric acute-onset neuropsychiatric syndromePaediatric autoimmune neuropsychiatric disorders associated with streptococcal infectionsPaediatricsPediatríaTrastorno obsesivo compulsive

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  • Poor response to standard treatments indicated a potential underlying PANS-PANDAS etiology.
  • Implications:

    • Emphasizes the need for increased medical community awareness regarding PANS-CANS.
    • Highlights the importance of early identification to mitigate long-term morbidity.
    • Suggests evaluating school-aged children with obsessive-compulsive or eating disorders for PANS-CANS.