Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ion Exchange01:17

Ion Exchange

633
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
633
Ion-Exchange Chromatography01:09

Ion-Exchange Chromatography

656
Ion-exchange chromatography, or IEC, is a technique for separating ions based on their affinity for the stationary phase. The stationary phase is a cross-linked polymer resin with covalently attached ionic functional groups. The functional groups can be either positively charged (cation exchangers) or negatively charged (anion exchangers). A cation exchanger consists of a polymeric anion and active cations, while an anion exchanger is a polymeric cation with active anions. The choice of...
656
Introduction to Membrane Proteins01:16

Introduction to Membrane Proteins

67.0K
The cell membrane, or plasma membrane, is an ever-changing landscape. It is described as a fluid mosaic where various macromolecules are embedded in the phospholipid bilayer. Among the macromolecules are proteins. The protein content varies across cell types. For example, mitochondrial inner membranes contain ~76% protein content, while myelin contains ~18% protein content. Individual cells contain many types of membrane proteins—red blood cells contain over 50—and different cell...
67.0K
Insertion of Multi-pass Transmembrane Proteins in the RER01:29

Insertion of Multi-pass Transmembrane Proteins in the RER

8.2K
The rough ER membrane synthesizes, assembles, and embeds transmembrane proteins in diverse topologies. These proteins function as transporters or channels and can remain in the ER membrane or are sent to the Golgi complex, lysosome, and cell membrane.
The multipass transmembrane proteins are the type IV integral membrane proteins with multiple topogenic sequences determining their spatial arrangement in the ER membrane. Nearly all multipass proteins lack a cleavable signal sequence and use...
8.2K
Potentiometry: Membrane Electrodes01:15

Potentiometry: Membrane Electrodes

710
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
710
Protein Translocation Machinery on the ER Membrane01:28

Protein Translocation Machinery on the ER Membrane

4.8K
The translocon complex situated on the ER membrane is the main gateway for the protein secretory pathway. It facilitates the transport of nascent peptides into the ER lumen and their insertion into the ER membrane.
Sec61 protein conducting channel
In eukaryotes, the translocon complex comprises a core heterotrimeric translocator channel called the Sec61 complex. This channel includes three transmembrane proteins, Sec61α, Sec61β, and Sec61γ, and is the largest subunit of the...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Homologous Self-Assembled Oligomers as Dual Anode/Cathode Interface Layers for Efficient Organic Photovoltaics.

ACS applied materials & interfaces·2026
Same author

Recent Progress in Organic Small-Molecule Antibacterial Agents.

Chembiochem : a European journal of chemical biology·2026
Same author

Light-triggered molecular mechanotherapy of tumor using membrane-mimicking conjugated oligoelectrolytes.

Science advances·2025
Same author

Wet chemically produced nanomaterials for soft wearable biosensors.

Nanoscale horizons·2025
Same author

Engineered multi-domain lipid nanoparticles for targeted delivery.

Chemical Society reviews·2025
Same author

Conductivity of Electropolymerized Thiophene Films: Effect of Fused-Ring Thiophenes as the Monomer.

ACS applied materials & interfaces·2025
Same journal

Fluorescent merocyanines: from fundamental properties to applications as molecular probes, in bioimaging and as emissive dye aggregates.

Chemical Society reviews·2026
Same journal

Direct impure water electrolysis at industrial scale.

Chemical Society reviews·2026
Same journal

Catalytic valorization of polyolefins: from catalysts and processes to reactors.

Chemical Society reviews·2026
Same journal

Designing stable π-radicals.

Chemical Society reviews·2026
Same journal

Antibacterial drug discovery: challenges and preclinical promises from synthetic small molecules.

Chemical Society reviews·2026
Same journal

Selective carbon-carbon bond cleavage involving alkene moieties.

Chemical Society reviews·2026
See all related articles

Related Experiment Video

Updated: Aug 19, 2025

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

8.6K

Membrane-intercalating conjugated oligoelectrolytes.

Cheng Zhou1,2, Geraldine W N Chia2, Ken-Tye Yong3

  • 1Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, 510640, P. R. China. czhou@scut.edu.cn.

Chemical Society Reviews
|November 30, 2022
PubMed
Summary
This summary is machine-generated.

Membrane-intercalating conjugated oligoelectrolytes (MICOEs) mimic lipid bilayers, enabling diverse biological applications. Their unique structure and design offer potential for advanced biomaterials in sensing, therapeutics, and more.

More Related Videos

Electrophoretic Crystallization of Ultrathin High-performance Metal-organic Framework Membranes
07:45

Electrophoretic Crystallization of Ultrathin High-performance Metal-organic Framework Membranes

Published on: August 16, 2018

10.0K
Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
05:47

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts

Published on: August 7, 2018

7.8K

Related Experiment Videos

Last Updated: Aug 19, 2025

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
08:06

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

8.6K
Electrophoretic Crystallization of Ultrathin High-performance Metal-organic Framework Membranes
07:45

Electrophoretic Crystallization of Ultrathin High-performance Metal-organic Framework Membranes

Published on: August 16, 2018

10.0K
Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts
05:47

Preparation of Polyoxometalate-based Photo-responsive Membranes for the Photo-activation of Manganese Oxide Catalysts

Published on: August 7, 2018

7.8K

Area of Science:

  • Biomaterials Science
  • Supramolecular Chemistry
  • Chemical Biology

Background:

  • Conjugated molecules have evolved into membrane-intercalating conjugated oligoelectrolytes (MICOEs).
  • MICOEs effectively biomimic lipid bilayers, allowing spontaneous insertion into synthetic and biological membranes.

Purpose of the Study:

  • To review the structural evolution and design principles of MICOEs.
  • To highlight the diverse applications of MICOEs in biological systems.
  • To discuss future research directions and opportunities for MICOEs.

Main Methods:

  • Analysis of the structural evolution of MICOEs from conjugated molecules.
  • Review of representative applications driven by MICOE molecular design.
  • Discussion of challenges and opportunities in MICOE research.

Main Results:

  • MICOEs demonstrate versatile applications including bioproduction, biocatalysis, biosensing, and therapeutics.
  • The modular design of MICOEs is key to their functional versatility.
  • MICOEs represent promising unconventional materials for biological applications.

Conclusions:

  • MICOEs are effective lipid bilayer biomimetics with significant potential in various biological fields.
  • Understanding MICOE design principles is crucial for unlocking their full application range.
  • Further research into MICOEs promises novel advancements in biomaterials and biotechnology.