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Ratiometric Zinc Biosensor Based on Bioluminescence Resonance Energy Transfer: Trace Metal Ion Determination with

Evgenia G Matveeva1, Andrea K Stoddard2, Hui-Hui Zeng1

  • 1Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene St., Baltimore, MD 21201, USA.

International Journal of Molecular Sciences
|December 11, 2022
PubMed
Summary

A new biosensor uses a fusion protein and bioluminescence resonance energy transfer (BRET) to detect zinc ions. This method offers sensitive, selective, and real-time monitoring of free zinc in biological and analytical chemistry.

Keywords:
BRETbioluminescencebiosensorcarbonic anhydrasemolecular imagingzinc

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