Discussion on treatment courses of brucellosis with spondylitis - a report of two cases
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Updated: Aug 17, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Zhi Yang1, Weigang Wu1, Pengcheng Ou1
1Department of Infectious Diseases, The Second Affiliated Clinical Medical College of Jinan University,Shenzhen People's Hospital, Shenzhen 518000, China.
Abstract:
Human Brucellosis is a zoonotic contagious disease caused by Brucella infection and is common throughout the world, which can travel through the bloodstream to various organs. Brucellar spondylitis(BS) is the foremost cause of brucellosis's debilitating and disabling complications. We report two sisters with brucellosis complicated by lumbar spondylodiscitis accompanied by cold abscess formation. The diagnosis was based on their symptoms, epidemiological characteristics, laboratory and magnetic resonance imaging(MRI) results. Our therapeutic strategy in these two cases indicate that drug combination and prolongation of the use of antibiotics is a therapeutic strategy worthy of popularizing to reach a greater clearance rate of the infection.
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