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Fulminans Purpura due to Morganella morganii
Mariana Guerra1, Daniela Marado1
1Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
Abstract:
Purpura fulminans (PF) is a dermatological manifestation of a life-threatening condition characterized by disseminated intravascular coagulation and endovascular thrombosis. The idiopathic/infectious form is the most common and usually associated with infection by Neisseria meningitidis or Streptococcus pneumoniae. We describe a case of Morganella morganii-induced bacteriaemia complicated with PF in an individual who had undergone a recent urinary tract infection intervention. The patient presented with purpuric skin lesions, fever and hypotension but had no alterations in coagulation parameters or disseminated intravascular coagulation. Aggressive early resuscitation, intravenous antibiotics and wound care were essential to a favourable response.
Learning Points:
Purpura fulminans is a dermatological manifestation of an underlying life-threatening condition, and is characterized by disseminated intravascular coagulation and skin necrosis.It is a morbid and potentially fatal condition that can be a cutaneous manifestation of Morganella morganii bacteraemia.Early identification and accurate diagnosis of the underlying cause can help minimize morbidity and mortality; management should be tailored to the individual, with the use of intravenous antibiotics, necrotic skin excision and aggressive early resuscitation.
Insights
Purpura fulminans, a severe skin condition, can be caused by Morganella morganii bacteremia. Early resuscitation and antibiotics are crucial for managing this life-threatening condition.
Area of Science:
- Dermatology
- Infectious Diseases
- Critical Care Medicine
Background:
- Purpura fulminans (PF) is a severe dermatological manifestation linked to disseminated intravascular coagulation and thrombosis.
- The most frequent forms of PF are idiopathic or infectious, often associated with Neisseria meningitidis or Streptococcus pneumoniae.
- This case highlights a rare presentation of PF secondary to Morganella morganii bacteremia.
Purpose of the Study:
- To report a case of Purpura fulminans secondary to Morganella morganii bacteremia.
- To emphasize the importance of early diagnosis and management in this potentially fatal condition.
- To discuss the clinical presentation and treatment of PF in the context of a recent urinary tract infection intervention.
Main Methods:
- Case report detailing a patient with Purpura fulminans.
- Clinical presentation including purpuric lesions, fever, and hypotension.
- Management involved aggressive early resuscitation, intravenous antibiotics, and wound care.
Main Results:
- The patient presented with Purpura fulminans despite normal coagulation parameters and no evidence of disseminated intravascular coagulation.
- Morganella morganii was identified as the causative agent of bacteremia.
- The patient showed a favorable response to prompt medical intervention.
Conclusions:
- Purpura fulminans can be a cutaneous manifestation of Morganella morganii bacteremia.
- Early identification and tailored management, including antibiotics and resuscitation, are vital for improving outcomes.
- This case underscores the need to consider diverse pathogens in the etiology of Purpura fulminans.
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