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Transvenous Lead Extraction in Pediatric Patients - Is It the Same Procedure in Children as in Adults?
Andrzej Kutarski1, Maria Miszczak-Knecht2, Monika Brzezinska2
1Department of Cardiology, Medical University Lublin.
Insights
Transvenous lead extraction (TLE) in children is more complex and less successful than in adults due to fibrous tissue buildup. This impacts pediatric cardiac implantable electronic device management.
Area of Science:
- Pediatric Cardiology
- Electrophysiology
- Medical Device Technology
Background:
- Cardiac implantable electronic devices (CIEDs) are uncommon in children.
- Transvenous lead extraction (TLE) is a necessary procedure for pediatric CIEDs.
- TLE in children presents unique challenges compared to adults.
Purpose of the Study:
- To determine the differences in TLE between pediatric and adult populations.
- To analyze risk factors, procedural complexity, and effectiveness of TLE in children versus adults.
Main Methods:
- Post hoc analysis of TLE data from 63 children (≤18 years) and 2,659 adults (≥40 years).
- Comparison of risk factors, procedure complexity, and effectiveness between the two groups.
Main Results:
- Children had longer implant durations and longer extraction times per lead.
- Pediatric TLE involved more technical difficulties and lower complete radiographic and procedural success rates.
- Lead dysfunction was the primary indication for TLE in children.
Conclusions:
- TLE in children is more complex, time-consuming, and arduous.
- Lower procedural success in pediatric TLE is linked to strong fibrous tissue formation around leads.
- Management of pediatric CIEDs requires consideration of these TLE-specific challenges.
Background:
Cardiac implantable electronic devices (CIED) are very rare in the pediatric population. In children with CIED, transvenous lead extraction (TLE) is often necessary. The course and effects of TLE in children are different than in adults. Thus, this study determined the differences and specific characteristics of TLE in children vs. adults.
Methods And Results:
A post hoc analysis of TLE data in 63 children (age ≤18 years) and 2,659 adults (age ≥40 years) was performed. The 2 groups were compared with respect to risk factors, procedure complexity, and effectiveness. In children, the predominant pacing mode was a single chamber ventricular system and lead dysfunction was the main indication for lead extraction. The mean implant duration before TLE was longer in children (P=0.03), but the dwell time of the oldest extracted lead did not differ significantly between adults and children. The duration (P=0.006) and mean extraction time per lead (P<0.001) were longer in children, with more technical difficulties during TLE in the pediatric group (P<0.001). Major complications were more common, albeit not significantly, in children. Complete radiographic and procedural success were significantly lower in children (P<0.001).
Conclusions:
TLE in children is frequently more complex, time consuming, and arduous, and procedural success is more often lower. This is related to the formation of strong fibrous tissue surrounding the leads in pediatric patients.
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