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Updated: Aug 16, 2025

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
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Three Novel Antisense Overlapping Genes in E. coli O157:H7 EDL933

Franziska Graf1,2, Barbara Zehentner2, Lea Fellner2

  • 1Core Facility Microbiome, ZIEL - Institute for Food & Health, Technische Universität München, Freising, Germany.

Microbiology Spectrum
|December 19, 2022
PubMed
Summary

Researchers discovered novel overlapping genes in bacteria, challenging previous assumptions about genome coding capacity. These genes, verified through ribosome profiling, demonstrate biological functionality and suggest bacterial genomes are more complex than currently annotated.

Keywords:
EHEC O157:H7competitive growth assaysoverlapping genesphenotypeprokaryotic genomesproteinribosome footprinting

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